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Brucellosis

Maltese fever, brucellosis or brucellosis is an animal disease that affects many animals and may then spread to humans in many ways.

A 5-year-old child with acute lymphoblastic leukemia (ALL) in remission is due for MMR and varicella vaccines. What is the best approach?


A) Administer both vaccines immediately

B) Administer only the inactivated vaccines

C) Postpone MMR and varicella until 3 months after chemotherapy ends

D) Give varicella but delay MMR

✅ Correct Answer: C) Postpone MMR and varicella until 3 months after chemotherapy ends.


Explanation: Live vaccines (e.g., MMR and varicella) should not be administered during chemotherapy or within 3 months of completing immunosuppressive therapy due to the risk of uncontrolled viral replication. Inactivated vaccines can be given, but they may have reduced efficacy during immunosuppression.

📖 Source:

● American Academy of Pediatrics (AAP). "Immunization in Immunocompromised Children: Guidelines and Recommendations." AAP, 2023.

● Infectious Diseases Society of America (IDSA). "Vaccination of the Immunocompromised Host: Best Practices." IDSA, 2022

Maltese disease complications

Maltese fever has some complications that may be serious, including:

  • Complications of the nervous system include schizophrenia, inflammation of brain cells, cerebrospinal fluid, etc. These complications are serious and may damage brain cells and convulsions.
  • Heart complications include inflammation of the valves and sometimes myocardium.
  • Hepatitis.
  • Inflammation of the testes and the epididymis.


Maltese disease complications

  • If the patient has noticed the continued heat for more than ten days with the presence of the joints, the doctor should see the necessary tests and then take the appropriate treatment.
  • The delay in diagnosis and failure to take appropriate treatment leads to the possibility of complications and failure to respond to treatment.

Protection:

  • Do not use unpasteurized milk or its derivatives…
  • Pasteurization is not just heating or boiling, but is an integrated process of heating and cooling times specific and organized.
  • Take care when washing your hands thoroughly with soap and water.
  • Inspect the animals regularly by the competent veterinarian and give them the necessary vaccinations.
  • Take into account not to mix animals from different factions with each other and take care of their cleanliness and cleanliness of their estates.